Skin Biology
H > Contract Research Service > Skin Biology

Tego Science provides Neoderm-based contract research services to screen substances for its safe and effective usage on human skin.

The areas covered are cosmetics, pharmaceuticals and medical devices.

Tests
Test Description Neoderm® Test method
Skin Irritation Assesses the skin irritation level of the test substance through measurement of cell viability and IL-1α Neoderm®-ED
Neoderm®-E
MTT assay, ELISA assay
Skin Permeation Assesses the permeability of the substance Neoderm®-ED
Neoderm®-E
Franz-diffusion cell
HPLC
Regeneration/
Elasticity
Analyzes the keratinocyte proliferation as well as cytokine and collagen formation following application of the test substance Neoderm®-ED
Neoderm®-M
ELISA assay
Immunofluorescence stain
Wound Healing Analyzes re-epithelialization after application of the test substance Neoderm®-ED H&E stain
Crystal violet stain
Lightening Assesses the lightening effectiveness of the test substance through qualitative and quantitative analysis of melanogenesis Neoderm®-ME
Neoderm®-M
DOPA stain
Fontana-Masson stain
Tyrosinase activity assay
Melanin Content assay

* Eye irritation and photo-toxicity assays are currently under development.